For Providers

What Is Anchor?

The Anal Cancer HSIL Outcomes Research study is a National Institutes of Health (NIH)-funded study with the primary objective of determining whether treating anal high-grade squamous intraepithelial lesions (HSIL) is effective in reducing the incidence of anal cancer in people living with HIV, just as screening for and treatment of similar lesions in the cervix reduces the incidence of cervical cancer.

WHAT ARE THE INCLUSION CRITERIA?

ANCHOR study inclusion criteria include:

  • Men, women, transgender folks living with HIV
  • 35 years of age and older
  • Biopsy-proven anal high-grade squamous intraepithelial lesion (HSIL), as determined at an ANCHOR screening visit

WHAT ARE THE EXCLUSION CRITERIA?

Among ANCHOR study exclusion criteria are:

  • History of anal, penile, vulvar, vaginal, or cervical cancer
  • Being on chronic systemic immunomodulatory agents
  • Inability to comply with the protocol (e.g. anoscopy)